Specific malabsorption of vitamin B12 in Down's syndrome.

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Specific malabsorption of vitamin B12 in Down's syndrome.

A 3 year old girl with Down's syndrome became lethargic and withdrawn, and investigations showed a specific malabsorption of vitamin B12 without proteinuria.

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Imerslund-Gräsbeck syndrome (selective vitamin B12 malabsorption with proteinuria)

Imerslund-Gräsbeck syndrome (IGS) or selective vitamin B(12) (cobalamin) malabsorption with proteinuria is a rare autosomal recessive disorder characterized by vitamin B(12) deficiency commonly resulting in megaloblastic anemia, which is responsive to parenteral vitamin B(12) therapy and appears in childhood. Other manifestations include failure to thrive and grow, infections and neurological d...

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Omeprazole therapy causes malabsorption of cyanocobalamin (vitamin B12)

OBJECTIVE To evaluate protein-bound cyanocobalamin (vitamin B12) absorption before and after omeprazole (Prilosec) therapy in healthy male volunteers. DESIGN Clinical trial in which each volunteer served as his own control. SETTING Outpatient department of a university medical center. PARTICIPANTS Ten healthy, male volunteers 22 to 50 years old. INTERVENTION Each participant had a modif...

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Granulomatous gastritis, iron deficiency, vitamin B12 malabsorption and immunoglobulin deficiency.

ODEBURG, B. (1965) Eosinophilic leukaemia and disseminated eosinophilic collagen disease-a disease entity? Acta medica scandinavica, 177, 129. PHILLIPS, P.E. & CHRISTIAN, C.L. (1973) Virus antibodies in SLE and other connective tissue diseases. Annals of the Rheumatic Diseases, 32, 480. PIERCE, L.E., HOSSEINIAN, A.H. & CONSTANTINE, A.B. (1967) Disseminated eosinophilic collagen disease. Blood, ...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1986

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.61.5.514